San Francisco 49ers fans would certainly agree that Trey Lance has been the team’s worst draft pick of the 2020s.
When NFL Draft expert Matt Holder of Bleacher Report released an article titled, “Re-Drafting Every NFL Team’s Worst Draft Pick Over Last 5 Years”, Niners fans expected to see Lance as the 49ers entry. It would have been more surprising if Holder didn’t pick him.
But Holder went even further than calling Lance the worst pick by the 49ers since 2020.

“Lance might be the biggest draft bust in 49ers’ history,” Holder wrote. “Not only did the organization use a high pick on him, but it traded three first-round picks and a third-rounder to get him. That comes out to one draft pick per start that the North Dakota State product had in San Francisco.”
As Holder mentioned, the 49ers spent not only their 2021 first round pick on Lance, but traded away their 2022 and 2023 first rounders as well, sacrificing a shot at blue chip superstars two years in a row for a guy who’d ultimately only play four bad games for the team.
The 49ers’ awful luck was balanced out with great luck the next year, drafting Brock Purdy with the last pick in the draft and getting a superstar out of him.
But the fact of the matter remains that the 49ers would like to have those first rounders back.
Who Could the 49ers Have Drafted Instead of Lance?
In Holder’s article, he assumed the 49ers didn’t make the trade up at all if Lance wasn’t the guy they were going for.
In that case, he tabbed star offensive tackle Rashawn Slater as the guy the 49ers should have taken at No. 12 overall.